GAMBARAN ANTIBODI DENGAN METODE DCT (Direct Coombs Test) PADA PASIEN GAGAL GINJAL KRONIK YANG MENJALANI HEMODIALISA

Agustina, Dian, G1C216025 (2017) GAMBARAN ANTIBODI DENGAN METODE DCT (Direct Coombs Test) PADA PASIEN GAGAL GINJAL KRONIK YANG MENJALANI HEMODIALISA. Sarjana / Sarjana Terapan (S1/D4) thesis, ["eprint_fieldopt_institution_Universitas Muhammadiyah Semarang" not defined].

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Abstract

Pasien gagal ginjal kronik yang menjalani hemodialisa akan mendapatkan transfusi darah berulang. Hal ini dikarenakan pasien gagal ginjal kronik mengalami penurunan produksi hormon EPO (Eritropoeitin). Pemberian transfusi darah dapat memicu pembentukan antibodi di permukaan sel darah merah, diperlukan uji untuk pemeriksaan antibodi. Uji yang digunakan adalah DCT (Direct Coombs Test) betujuan untuk mendeteksi antibodi pada permukaan sel darah merah. Tujuan penelitian ini adalah untuk mengetahui hasil gambaran antibodi dengan metode DCT (Direct Coombs Test) pada pasien gagal ginjal yang menjalani hemodialisa. Metode penelitian yang digunakan adalah deskriptif dimana sebanyak 33 sampel pasien gagal ginjal kronik yang menjalani hemodialisa di Rumah Sakit Roemani Muhammadiyah Semarang. Hasil gambaran antibodi metode DCT (Direct Coombs Test) pada pasien gagal ginjal kronik yang menjalani hemodialisa adalah AHG positif 2 sampel (6 %), AHG negatif 31 sampel (94 %) dan IgG positif 4 sampel (12 %), IgG negatif 29 sampel (88 %). Kesimpulan dari hasil penelitian ini bahwa gambaran antibodi menggunakan reagensia AHG dan IgG sebagian kecil positif. Kata kunci : Antibodi, DCT (Direct Coombs Test), Hemodialisa Patient with chronic renal failure who undergo hemodialysis will get recurrent blood transfusions. This is patients with chronic renl failure experience a decrease in EPO (Eritropoeitin) hormone production. Giving blood transfusions can trigger the formation of antibodies on the surface of red blood cells, testing is needed for antibody testing. The test used is DCT (Direct Coombs Test) aim to detect antibodies on the surface of red blood cells. The purpose of this study was to determine the result of antibody image with DCT method in patients with renal failure who underwent hemodialysis. The research method used is descriptive where as many as 33 samples of patients with chronic renal failure who underwent hemodialysis at Roemani Muhammdiyah Hospital Semarang. The results of DCT antibody feature in patient with chronic renal failure who underwent hemodialysis were positive AHG 2 samples (6 %), negative AHG 31 samples 94% and IgG positive 4 samples (12 %), negative IgG 29 samples (88 %). Conclusions from the results of this study that the antibody image using the reagents AHG and IgG are small positive. Keywords: Antibody, DCT (Direct Coombs Test), Hemodialysis

Item Type: Thesis (Sarjana / Sarjana Terapan (S1/D4) )
Contributors Thesis: 033/D4Ana/XI/2017
Subjects: R Medicine > Health Analyst
Divisions: Faculty of Nursing and Health > D4 Health Analyst
Depositing User: perpus unimus
Date Deposited: 28 Dec 2017 07:50
Last Modified: 12 Apr 2018 07:52
URI: http://repository.unimus.ac.id/id/eprint/1263

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