UJI DAYA HAMBAT EKSTRAK ETHANOL DAUN CENGKEH (Syzygium aromaticum L) TERHADAP PERTUMBUHAN Cryptococcus neoformans

Salufo,Nurhasanah A., G1C218278 (2019) UJI DAYA HAMBAT EKSTRAK ETHANOL DAUN CENGKEH (Syzygium aromaticum L) TERHADAP PERTUMBUHAN Cryptococcus neoformans. Undergraduate thesis, Universitas Muhammadiyah Semarang.

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Abstract

ABSTRAK Daun cengkeh (Syzygium aromaticum L) merupakan salah satu tanaman yang sering dimanfaatkan sebagai obat tradisional. Daun cengkeh memiliki kandungan senyawa eugenol, flavonoid, saponin, dan tanin yang bersifat antijamur. Cryptococcus neoformans merupakan jamur uniseluler yang dapat menimbulkan penyakit sistemik, menginfeksi organ bagian dalam (terutama paru) dan dapat menyebar ke selaput otak (meningitis). Tujuan penelitian ini untuk mengetahui daya hambat ekstrak ethanol daun cengkeh terhadap pertumbuhan Cryptococcus neoformans. Penelitian ini merupakan penelitian eksperimental dengan pengujian menggunakan metode ekstraksi maserasi dan difusi sumuran dengan menggunakan isolat murni Cryptococcus neoformans dari 3 jenis sampel kotoran burung.. Hasil penelitian menunjukan bahwa uji daya hambat ekstrak ethanol daun cengkeh pada konsentrasi 10%, 20%, 30%, dan 40% dapat menghambat pertumbuhan Cryptococcus neoformans dengan pengujian sebanyak 3 kali pengulangan dengan hasil rata-rata 11 mm pada konsentrasi 5%, 13,6 mm pada konsentrasi 20%, 16,3 mm pada konsentrasi 30%, dan 19 mm pada konsentrasi 40%. Dari hasil penelitian yang dilakukan dapat disimpulkan bahwa ekstrak ethanol daun cengkeh memiliki daya hambat terhadap pertumbuhan Cryptococcus neoformans. Kata Kunci : Daya hambat, Ekstrak ethanol daun cengkeh, Cryptococcus neoformans   Inhibition Test of Ethanol Extract of Clove Leaves (Syzygium aromaticum L) on the Growth of Cryptococcus neoformans Nurhasanah A. Salufo1, Sri Sinto Dewi2, Arya Iswara2 1. DIV Health Analyst Study Program Faculty of Nursing and Health Sciences Muhammadiyah University of Semarang 2. Microbiology Laboratory, Faculty of Nursing and University Health Sciences Muhammadiyah Semarang ABSTRACT Clove leaf (Syzygium aromaticum L) is a plant that is often used as traditional medicine. Clove leaves contain eugenol compounds, flavonoids, saponins, and tannins that are antifungal. Cryptococcus neoformans is a unicellular fungus that can cause systemic disease, infect internal organs (especially lungs) and can spread to the lining of the brain (meningitis). The purpose of this study was to determine the inhibition of clove leaf ethanol extract on the growth of Cryptococcus neoformans. This study is an experimental study using maceration extraction and diffusion well testing using pure Cryptococcus neoformans isolates from 3 types of bird droppings. The results showed that the inhibitory test of clove leaf ethanol extract at concentrations of 10%, 20%, 30% and 40% can inhibit the growth of Cryptococcus neoformans by testing 3 repetitions with an average yield of 11 mm at a concentration of 5%, 13.6 mm at a concentration of 20%, 16.3 mm at a concentration of 30%, and 19 mm at a concentration of 40 %. From the results of research conducted it can be concluded that the ethanol extract of clove leaves has inhibitory effect on the growth of Cryptococcus neoformans. Keywords: Inhibitory power, Clove leaf ethanol extract, Cryptococcus neoformans

Item Type: Thesis (Undergraduate)
Call Number: 009/D4Ana/I/2020
Subjects: R Medicine > Health Analyst
Divisions: Faculty of Nursing and Health > D4 Health Analyst
Depositing User: perpus unimus
Date Deposited: 13 Feb 2020 03:17
Last Modified: 13 Feb 2020 03:19
URI: http://repository.unimus.ac.id/id/eprint/3557

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